Fans may relieve breathlessness associated with advanced cancers

Blowing air from a fan into the face of patients with advanced cancer experiencing breathlessness, and other nonpharmacologic interventions, may offer symptom relief, according to new research directed by Johns Hopkins Kimmel Cancer Center investigators. On the other hand, the investigators found medications, such as opioids, had limited impact in improving breathlessness. In a systematic […]

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Hematoxylin as a killer of CALR mutant cancer cells

Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, adjunct principal investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have now identified hematoxylin as […]

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Beta-blockers display anti-inflammatory effects in advanced liver disease

Approximately 170,000 people die every year in Europe from the direct consequences of advanced chronic liver disease (cirrhosis). In Austria, cirrhosis of the liver is usually due to a fatty liver resulting from excessive alcohol consumption or overeating and/or poor diet and—thanks to effective antiviral therapies—less common due to viral hepatitis. Chronic liver damage leads […]

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Immunotherapy improves responses without reducing quality of life in early breast cancer

Adding an immune checkpoint inhibitor to the standard chemotherapy regimen for patients with early-stage breast cancer places no greater burden on patients’ ability to perform day-to-day activities than chemotherapy alone, new research by Dana-Farber/Brigham and Women’s Cancer Center investigators shows. The report, coupled with earlier findings that combining checkpoint inhibitors with chemotherapy can increase response […]

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